High density lipoprotein protects against polymicrobe-induced sepsis in mice.

Guo, Ling; Ai, Junting; Zheng, Zhong; Howatt, Deborah A; Daugherty, Alan; Huang, Bin; Li, Xiang-An

Guo, Ling; Ai, Junting; Zheng, Zhong; Howatt, Deborah A; Daugherty, Alan; Huang, Bin; Li, Xiang-An.

Affiliation

Guo L; Department of Pediatrics, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA.

J Biol Chem ; 288(25): 17947-53, 2013 Jun 21.

Article in En | MEDLINE | ID: mdl-23658016

Subject(s)

Apolipoprotein A-I/immunology; Bacterial Infections/immunology; Lipoproteins, HDL/immunology; Sepsis/immunology; Animals; Apolipoprotein A-I/genetics; Bacterial Infections/complications; Cecum/surgery; Corticosterone/blood; Corticosterone/immunology; Interleukin-6/blood; Interleukin-6/immunology; Ligation; Lipopolysaccharides/blood; Lipopolysaccharides/immunology; Lipopolysaccharides/metabolism; Lipoproteins/immunology; Lipoproteins/metabolism; Lipoproteins, HDL/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neutrophil Infiltration/immunology; Peritoneum/immunology; Peritoneum/metabolism; Punctures; Sepsis/etiology; Sepsis/mortality; Survival Rate; Tumor Necrosis Factor-alpha/blood; Tumor Necrosis Factor-alpha/immunology

Key words

Apolipoprotein A-I; Cecal Ligation and Puncture; Dyslipidemia; High Density Lipoprotein (HDL); Immunology; Lipopolysaccharide (LPS); SCARB1; Scavenger Receptor BI; Sepsis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Infections / Apolipoprotein A-I / Sepsis / Lipoproteins, HDL Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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