The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells.

Saito, Syuhei; Hosoda, Nao; Hoshino, Shin-ichi

Saito, Syuhei; Hosoda, Nao; Hoshino, Shin-ichi.

Affiliation

Saito S; Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan.

J Biol Chem ; 288(24): 17832-43, 2013 Jun 14.

Article in En | MEDLINE | ID: mdl-23667253

Subject(s)

GTP-Binding Proteins/physiology; HSP70 Heat-Shock Proteins/physiology; Microfilament Proteins/metabolism; Peptide Elongation Factors/physiology; RNA Stability; RNA, Messenger/metabolism; Endonucleases; Exosome Multienzyme Ribonuclease Complex/genetics; Exosome Multienzyme Ribonuclease Complex/metabolism; Gene Expression; Gene Knockdown Techniques; Half-Life; HeLa Cells; Humans; Nuclear Proteins; Protein Binding; Protein Biosynthesis; RNA, Messenger/genetics; RNA, Small Interfering/genetics; RNA-Binding Proteins/metabolism

Key words

Exosomes; Hbs1; Non-stop Decay; RNA Turnover; Ribosomes; Translation Release Factors; eRF3; mRNA Decay

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / Peptide Elongation Factors / HSP70 Heat-Shock Proteins / GTP-Binding Proteins / RNA Stability / Microfilament Proteins Limits: Humans Language: En Journal: J Biol Chem Year: 2013 Document type: Article Affiliation country: Japan Country of publication: United States

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