Essential role of NADPH oxidase-dependent reactive oxygen species generation in regulating microRNA-21 expression and function in prostate cancer.

Jajoo, Sarvesh; Mukherjea, Debashree; Kaur, Tejbeer; Sheehan, Kelly E; Sheth, Sandeep; Borse, Vikrant; Rybak, Leonard P; Ramkumar, Vickram

Jajoo, Sarvesh; Mukherjea, Debashree; Kaur, Tejbeer; Sheehan, Kelly E; Sheth, Sandeep; Borse, Vikrant; Rybak, Leonard P; Ramkumar, Vickram.

Affiliation

Jajoo S; 1 Department of Pharmacology, Southern Illinois University School of Medicine , Springfield, Illinois.

Antioxid Redox Signal ; 19(16): 1863-76, 2013 Dec 01.

Article in En | MEDLINE | ID: mdl-23682737

Subject(s)

Gene Expression Regulation, Neoplastic; MicroRNAs/genetics; MicroRNAs/metabolism; NADPH Oxidases/metabolism; Prostatic Neoplasms/genetics; Prostatic Neoplasms/pathology; Reactive Oxygen Species/metabolism; Animals; Apoptosis Regulatory Proteins/biosynthesis; Apoptosis Regulatory Proteins/genetics; Apoptosis Regulatory Proteins/metabolism; Humans; Male; Mice; Mice, SCID; NADPH Oxidases/antagonists & inhibitors; Neoplasm Invasiveness/genetics; Prostatic Neoplasms/enzymology; Prostatic Neoplasms/metabolism; RNA, Small Interfering/administration & dosage; RNA, Small Interfering/metabolism; RNA-Binding Proteins/biosynthesis; RNA-Binding Proteins/genetics; RNA-Binding Proteins/metabolism; Serpins/biosynthesis; Serpins/genetics; Serpins/metabolism; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Gene Expression Regulation, Neoplastic / Reactive Oxygen Species / NADPH Oxidases / MicroRNAs Limits: Animals / Humans / Male Language: En Journal: Antioxid Redox Signal Journal subject: METABOLISMO Year: 2013 Document type: Article Country of publication: United States

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