Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis.

Van Beneden, Katrien; Geers, Caroline; Pauwels, Marina; Mannaerts, Inge; Wissing, Karl M; Van den Branden, Christiane; van Grunsven, Leo A

Van Beneden, Katrien; Geers, Caroline; Pauwels, Marina; Mannaerts, Inge; Wissing, Karl M; Van den Branden, Christiane; van Grunsven, Leo A.

Affiliation

Van Beneden K; Department of Human Anatomy, Liver Cell Biology Lab, Vrije Universiteit Brussel, Brussels, Belgium. kvbenede@vub.ac.be

Toxicol Appl Pharmacol ; 271(2): 276-84, 2013 Sep 01.

Article in En | MEDLINE | ID: mdl-23707763

Subject(s)

Histone Deacetylase Inhibitors/therapeutic use; Hydroxamic Acids/therapeutic use; Kidney Diseases/drug therapy; Valproic Acid/therapeutic use; Acetylation; Animals; Doxorubicin; Female; Fibrosis; Glomerulosclerosis, Focal Segmental/chemically induced; Glomerulosclerosis, Focal Segmental/pathology; Immunohistochemistry; Inflammation/chemically induced; Inflammation/pathology; Kidney/pathology; Kidney Diseases/chemically induced; Kidney Diseases/pathology; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Neutrophil Infiltration; RNA, Messenger/biosynthesis; RNA, Messenger/genetics

Key words

Adriamycin; Glomerulosclerosis; Histone deacetylase; Proteinuria; Trichostatin A; Valproic acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Valproic Acid / Histone Deacetylase Inhibitors / Hydroxamic Acids / Kidney Diseases Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2013 Document type: Article Affiliation country: Belgium Country of publication: United States

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