Determination of cefdinir levels in rat plasma and urine by high-performance liquid chromatography-tandem mass spectrometry: application to pharmacokinetics after oral and intravenous administration of cefdinir.

Jin, Hyo-Eon; Kim, In-Bong; Kim, Chong-Kook; Maeng, Han-Joo

Jin, Hyo-Eon; Kim, In-Bong; Kim, Chong-Kook; Maeng, Han-Joo.

Affiliation

Jin HE; College of Pharmacy, Seoul National University, Seoul, Republic of Korea.

Biomed Chromatogr ; 27(11): 1423-30, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23712418

Subject(s)

Anti-Bacterial Agents/blood; Anti-Bacterial Agents/urine; Cephalosporins/blood; Cephalosporins/urine; Chromatography, High Pressure Liquid/methods; Tandem Mass Spectrometry/methods; Administration, Intravenous; Administration, Oral; Animals; Anti-Bacterial Agents/administration & dosage; Cefdinir; Cephalosporins/administration & dosage; Limit of Detection; Male; Rats; Rats, Sprague-Dawley

Key words

LC-MS/MS; cefdinir; pharmacokinetics; plasma; rat; urine

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cephalosporins / Chromatography, High Pressure Liquid / Tandem Mass Spectrometry / Anti-Bacterial Agents Limits: Animals Language: En Journal: Biomed Chromatogr Year: 2013 Document type: Article Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google