[Mass spectrum characterization of five valepotriates by electrospray ionization tandem mass spectrometry].
Zhongguo Zhong Yao Za Zhi
; 38(4): 578-84, 2013 Feb.
Article
in Zh
| MEDLINE
| ID: mdl-23713287
ABSTRACT
OBJECTIVE:
To discuss mass spectrum characterization of five valepotriates including 'monoene' type (didrovaltrate), 'diene' type (valtrate, acevaltrate) and 'four-olefinic' type (baldrinal and homobaldrinal) by electrospray ionization tandem mass spectrometry (ESI-MS(n)).METHOD:
This study was carried out on the basis of electrospray ionization tandem mass spectrometric method and analysis of multistage fragments.RESULT:
The fragmentation patterns and structural assignment of 'monoene' type, 'diene' type and 'four-olefinic' type valepotriates in ESI-MSn under positive mode were summarized.CONCLUSION:
The compounds have a strong pyrolysis rules and it can provide reference date for valepotriates in rapid structural identification, quantitative analysis and pharmacokinetic study.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drugs, Chinese Herbal
/
Spectrometry, Mass, Electrospray Ionization
/
Iridoids
/
Tandem Mass Spectrometry
Language:
Zh
Journal:
Zhongguo Zhong Yao Za Zhi
Journal subject:
FARMACOLOGIA
/
TERAPIAS COMPLEMENTARES
Year:
2013
Document type:
Article
Affiliation country:
China