The influence of phospho-&#964; on dendritic spines of cortical pyramidal neurons in patients with Alzheimer's disease.

Merino-Serrais, Paula; Benavides-Piccione, Ruth; Blazquez-Llorca, Lidia; Kastanauskaite, Asta; Rábano, Alberto; Avila, Jesús; DeFelipe, Javier

The influence of phospho-τ on dendritic spines of cortical pyramidal neurons in patients with Alzheimer's disease.

Merino-Serrais, Paula; Benavides-Piccione, Ruth; Blazquez-Llorca, Lidia; Kastanauskaite, Asta; Rábano, Alberto; Avila, Jesús; DeFelipe, Javier.

Affiliation

Merino-Serrais P; Laboratorio Cajal de Circuitos Corticales (CTB), Universidad Politécnica de Madrid, Campus Montegancedo S/N, 28223 Pozuelo de Alarcón, Spain.

Brain ; 136(Pt 6): 1913-28, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23715095

Subject(s)

Alzheimer Disease/metabolism; Cerebral Cortex/metabolism; Dendritic Spines/metabolism; Pyramidal Cells/metabolism; tau Proteins/physiology; Alzheimer Disease/pathology; Cell Count/methods; Cerebral Cortex/pathology; Dendritic Spines/pathology; Humans; Phosphorylation/physiology; Pyramidal Cells/pathology

Key words

3D reconstruction; confocal microscopy; dendritic spine density and volume; hippocampal formation; intracellular injection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Cortex / Tau Proteins / Pyramidal Cells / Dendritic Spines / Alzheimer Disease Limits: Humans Language: En Journal: Brain Year: 2013 Document type: Article Affiliation country: Spain Country of publication: United kingdom

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