Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs.

Rao, Guan-hua; Liu, Hong-min; Li, Bao-wei; Hao, Jia-jie; Yang, Yan-lei; Wang, Ming-rong; Wang, Xiao-hui; Wang, Jun; Jin, Hai-jing; Du, Lei; Chen, Quan

Rao, Guan-hua; Liu, Hong-min; Li, Bao-wei; Hao, Jia-jie; Yang, Yan-lei; Wang, Ming-rong; Wang, Xiao-hui; Wang, Jun; Jin, Hai-jing; Du, Lei; Chen, Quan.

Affiliation

Rao GH; Tianjin Key Laboratory of Protein Sciences, College of Life Sciences, Nankai University, Tianjin 300071, China.

Acta Pharmacol Sin ; 34(6): 793-804, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23736004

Subject(s)

Antineoplastic Agents/pharmacology; Colorectal Neoplasms/drug therapy; Neoplastic Stem Cells/metabolism; Animals; Camptothecin/pharmacology; Cell Line, Tumor; Colorectal Neoplasms/genetics; Colorectal Neoplasms/pathology; Drug Design; Drug Resistance, Neoplasm; Female; Fluorouracil/pharmacology; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Hyaluronan Receptors/metabolism; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Molecular Targeted Therapy; Xenograft Model Antitumor Assays/methods

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Colorectal Neoplasms / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2013 Document type: Article Affiliation country: China Country of publication: United States

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