Functional neuroanatomy of body checking in people with anorexia nervosa.
Int J Eat Disord
; 46(7): 653-62, 2013 Nov.
Article
in En
| MEDLINE
| ID: mdl-23740734
OBJECTIVE: The neural correlates of body checking perceptions in eating disorders have not yet been identified. This functional Magnetic Resonance Imaging study examined the neuroanatomy involved in altered perception and identification with body checking in female with anorexia nervosa (AN). METHOD: Brain activation while viewing images depicting normal weight individuals involved in either body checking behavior or a neutral (noneating disorder) body action, was compared between 20 females with AN and 15 matched healthy controls (HC). RESULTS: Females with AN reported higher anxiety compared to HC during the body checking task. The level of anxiety positively correlated with body shape concern scores. People with AN had less activation in the medial prefrontal cortex (PFC) and right fusiform gyrus compared to HC in response to body checking compared to neutral action images. Body shape concern scores correlated negatively with medial PFC activation in AN group. DISCUSSION: This preliminary study with modest power suggests that AN patients have reduced activation in cortical areas associated with self-reference, body action perception, and social cognition in females with AN.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anxiety
/
Body Image
/
Anorexia Nervosa
/
Frontal Lobe
Type of study:
Prognostic_studies
/
Qualitative_research
Limits:
Adolescent
/
Adult
/
Female
/
Humans
Language:
En
Journal:
Int J Eat Disord
Year:
2013
Document type:
Article
Affiliation country:
United kingdom
Country of publication:
United States