Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans.

Ballou, Elizabeth Ripley; Selvig, Kyla; Narloch, Jessica L; Nichols, Connie B; Alspaugh, J Andrew

Ballou, Elizabeth Ripley; Selvig, Kyla; Narloch, Jessica L; Nichols, Connie B; Alspaugh, J Andrew.

Affiliation

Ballou ER; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.

Fungal Genet Biol ; 57: 58-75, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23748012

Subject(s)

Cryptococcus neoformans/growth & development; Cryptococcus neoformans/genetics; rac GTP-Binding Proteins/genetics; rac1 GTP-Binding Protein/genetics; Actins/metabolism; Cryptococcosis/genetics; Cryptococcosis/microbiology; Cryptococcus neoformans/pathogenicity; Humans; Morphogenesis; Reactive Oxygen Species/metabolism; Sequence Homology, Amino Acid; cdc42 GTP-Binding Protein/genetics; cdc42 GTP-Binding Protein/metabolism; rac GTP-Binding Proteins/metabolism; rac1 GTP-Binding Protein/metabolism; RAC2 GTP-Binding Protein

Key words

Cryptococcus neoformans; Hyphal growth; Paralogs; Polarization; ROS; Rac GTPase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rac GTP-Binding Proteins / Rac1 GTP-Binding Protein / Cryptococcus neoformans Limits: Humans Language: En Journal: Fungal Genet Biol Journal subject: GENETICA / MICROBIOLOGIA Year: 2013 Document type: Article Affiliation country: United States

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