TLR-independent neutrophil-derived IFN-Î³ is important for host resistance to intracellular pathogens.

Sturge, Carolyn R; Benson, Alicia; Raetz, Megan; Wilhelm, Cara L; Mirpuri, Julie; Vitetta, Ellen S; Yarovinsky, Felix

Sturge, Carolyn R; Benson, Alicia; Raetz, Megan; Wilhelm, Cara L; Mirpuri, Julie; Vitetta, Ellen S; Yarovinsky, Felix.

Affiliation

Sturge CR; Department of Immunology, University of Texas Southwestern Medical School, Dallas, TX 75390, USA.

Proc Natl Acad Sci U S A ; 110(26): 10711-6, 2013 Jun 25.

Article in En | MEDLINE | ID: mdl-23754402

Subject(s)

Host-Pathogen Interactions/immunology; Interferon-gamma/physiology; Neutrophils/immunology; Neutrophils/metabolism; Toll-Like Receptors/immunology; Animals; Host-Parasite Interactions/immunology; Immunity, Innate; Interferon-gamma/deficiency; Mice; Mice, Inbred C57BL; Mice, Knockout; Salmonella typhimurium/immunology; Salmonella typhimurium/pathogenicity; T-Lymphocytes/immunology; Toll-Like Receptors/deficiency; Toll-Like Receptors/genetics; Toxoplasma/immunology; Toxoplasma/pathogenicity

Key words

host defense; innate immunity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Toll-Like Receptors / Host-Pathogen Interactions / Neutrophils Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2013 Document type: Article Affiliation country: United States

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