Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells.

Yang, Jun; Li, Xiaohui; Li, Ying; Southwood, Mark; Ye, Lingying; Long, Lu; Al-Lamki, Rafia S; Morrell, Nicholas W

Yang, Jun; Li, Xiaohui; Li, Ying; Southwood, Mark; Ye, Lingying; Long, Lu; Al-Lamki, Rafia S; Morrell, Nicholas W.

Affiliation

Yang J; Dept. of Medicine, Level 5, Box 157 Addenbrooke's Hospitals, Hills Rd., Cambridge, CB2 0QQ, UK.. nwm23@cam.ac.uk.

Am J Physiol Lung Cell Mol Physiol ; 305(4): L312-21, 2013 Aug 15.

Article in En | MEDLINE | ID: mdl-23771884

Subject(s)

Bone Morphogenetic Proteins/metabolism; Inhibitor of Differentiation Proteins/metabolism; Myocytes, Smooth Muscle/metabolism; Pulmonary Artery/pathology; Animals; Bone Morphogenetic Protein Receptors, Type II/deficiency; Bone Morphogenetic Protein Receptors, Type II/metabolism; Cell Cycle/drug effects; Cell Proliferation/drug effects; Familial Primary Pulmonary Hypertension; Gene Expression Regulation/drug effects; Humans; Hypertension, Pulmonary/genetics; Hypertension, Pulmonary/pathology; Inhibitor of Differentiation Proteins/genetics; Lipopolysaccharides/pharmacology; Lung/pathology; Mice; Mice, Mutant Strains; Myocytes, Smooth Muscle/drug effects; Myocytes, Smooth Muscle/pathology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction/drug effects; Time Factors

Key words

Id; bone morphogenetic protein type II receptor; cell cycle; pulmonary arterial smooth muscle cell; pulmonary hypertension

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Artery / Bone Morphogenetic Proteins / Myocytes, Smooth Muscle / Inhibitor of Differentiation Proteins Limits: Animals / Humans Language: En Journal: Am J Physiol Lung Cell Mol Physiol Journal subject: BIOLOGIA MOLECULAR / FISIOLOGIA Year: 2013 Document type: Article Affiliation country: United kingdom Country of publication: United States

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