Adaptation to visual stimulation modifies the burst firing property of V1 neurons.
Dongwuxue Yanjiu
; 34(E3): E101-8, 2013 Jun.
Article
in En
| MEDLINE
| ID: mdl-23776003
ABSTRACT
The mean firing rate of visual cortical neurons is reduced after prolonged visual stimulation, but the underlying process by which this occurs as well as the biological significance of this phenomenon remains unknown. Computational neuroscience studies indicate that high-frequency bursts in stimulus-driven responses can be transmitted across synapses more reliably than isolated spikes, and thus may carry accurate stimulus-related information. Our research examined whether or not adaptation affects the burst firing property of visual cortical neurons by examining changes in the burst firing changes of V1 neurons during adaptation to the preferred visual stimulus. The results show that adaptation to prolonged visual stimulation significantly decreased burst frequency (bursts/s) and burst length (spikes/burst), but increased burst duration and the interspike interval within bursts. These results suggest that the adaptation of V1 neurons to visual stimulation may result in a decrease of feedforward response gain but an increase of functional activities from lateral and/or feedback connections, which could lead to a reduction in the effectiveness of adapted neurons in transmitting information to its driven neurons.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sensory Receptor Cells
/
Adaptation, Physiological
Limits:
Animals
Language:
En
Journal:
Dongwuxue Yanjiu
Year:
2013
Document type:
Article