Mesenchymal stem cells transplantation ameliorates glomerular injury in streptozotocin-induced diabetic nephropathy in rats via inhibiting macrophage infiltration.

Lv, Sha-Sha; Liu, Gang; Wang, Jian-Ping; Wang, Wei-Wei; Cheng, Jing; Sun, Ai-Li; Liu, Hai-Ying; Nie, Hui-Bin; Su, Mo-Ran; Guan, Guang-Ju

Lv, Sha-Sha; Liu, Gang; Wang, Jian-Ping; Wang, Wei-Wei; Cheng, Jing; Sun, Ai-Li; Liu, Hai-Ying; Nie, Hui-Bin; Su, Mo-Ran; Guan, Guang-Ju.

Affiliation

Lv SS; Shandong University, Jinan, Shandong, China.

Int Immunopharmacol ; 17(2): 275-82, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23791972

Subject(s)

Chemokine CCL2/metabolism; Diabetes Mellitus, Experimental/therapy; Diabetic Nephropathies/therapy; Kidney/metabolism; Macrophages/pathology; Mesenchymal Stem Cell Transplantation; Animals; Cell Movement; Cells, Cultured; Chemokine CCL2/genetics; Collagen Type I/metabolism; Creatinine/urine; Cytokines/genetics; Cytokines/metabolism; Diabetes Mellitus, Experimental/immunology; Diabetic Nephropathies/immunology; Down-Regulation; Female; Fibronectins/metabolism; Hepatocyte Growth Factor/metabolism; Inflammation Mediators/metabolism; Kidney/pathology; Rats; Rats, Wistar

Key words

Bone marrow mesenchymal stem cells; Diabetic rats; Inflammation; Macrophages; Nephropathy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemokine CCL2 / Mesenchymal Stem Cell Transplantation / Diabetes Mellitus, Experimental / Diabetic Nephropathies / Kidney / Macrophages Limits: Animals Language: En Journal: Int Immunopharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Year: 2013 Document type: Article Affiliation country: China Country of publication: Netherlands

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