A network of interorganellar communications underlies cellular aging.

Leonov, Anna; Titorenko, Vladimir I

Leonov, Anna; Titorenko, Vladimir I.

Affiliation

Leonov A; Department of Biology, Concordia University, Montreal, QC, Canada.

IUBMB Life ; 65(8): 665-74, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23818261

Subject(s)

Cellular Senescence/physiology; Organelles/metabolism; Animals; Cell Compartmentation/physiology; Cytosol/metabolism; Humans; Lysosomes/physiology; Mechanistic Target of Rapamycin Complex 1; Mitochondria/physiology; Models, Biological; Multiprotein Complexes/metabolism; Peroxisomes/physiology; Signal Transduction/physiology; TOR Serine-Threonine Kinases/metabolism; Vacuoles/physiology

Key words

an endomembrane system governing cellular aging; biomolecular networks of cellular aging; cell-autonomous mechanisms of organismal aging; cellular aging; interorganellar communications; lysosomes and vacuoles; mitochondria; peroxisomes; signaling network of cellular aging

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Organelles / Cellular Senescence Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: IUBMB Life Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2013 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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