Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart.

Harmancey, Romain; Vasquez, Hernan G; Guthrie, Patrick H; Taegtmeyer, Heinrich

Harmancey, Romain; Vasquez, Hernan G; Guthrie, Patrick H; Taegtmeyer, Heinrich.

Affiliation

Harmancey R; 1University of Texas Medical School at Houston, 6431 Fannin, MSB 1.246, Houston, TX 77030, USA. heinrich.taegtmeyer@uth.tmc.edu.

FASEB J ; 27(10): 3966-78, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23825227

Subject(s)

Fatty Acids/chemistry; Fatty Acids/metabolism; Insulin Resistance/physiology; Reperfusion Injury/metabolism; Animal Feed; Animals; Caprylates; Diet; Dietary Carbohydrates; Gene Expression Regulation; Glucose/metabolism; Insulin/metabolism; Ion Channels/genetics; Ion Channels/metabolism; Male; Mitochondrial Proteins/genetics; Mitochondrial Proteins/metabolism; Oxidation-Reduction; Proto-Oncogene Proteins c-akt/genetics; Proto-Oncogene Proteins c-akt/metabolism; Rats; Rats, Sprague-Dawley; Sucrose; Uncoupling Protein 3

Key words

cardiac function; high-sucrose diet; myocardial metabolism; type 2 diabetes; uncoupling proteins

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Reperfusion Injury / Fatty Acids Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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