Serum levels of neopterin during antimicrobial treatment for Mycobacterium ulcerans infection.
Am J Trop Med Hyg
; 89(3): 498-500, 2013 Sep.
Article
in En
| MEDLINE
| ID: mdl-23836576
ABSTRACT
Neopterin is closely associated with activation of the cellular immune system. Neopterin levels differed between controls and patients with Buruli ulcer disease. No differences between patients with or without paradoxical responses were observed. Therefore, neopterin has no value in detecting paradoxical responses among patients with limited Buruli ulcer disease. Neopterin levels were lower in patients receiving clarithromycin. This finding might indicate a slower cellular immune recovery, with possible consequences in future therapy with clarithromycin.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Clarithromycin
/
Neopterin
/
Buruli Ulcer
/
Anti-Bacterial Agents
Type of study:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Am J Trop Med Hyg
Year:
2013
Document type:
Article
Affiliation country:
Netherlands