Neurological and muscular manifestations associated with influenza B infection in children.
Pediatr Neurol
; 49(2): 97-101, 2013 Aug.
Article
in En
| MEDLINE
| ID: mdl-23859854
ABSTRACT
BACKGROUND:
Influenza viruses have been associated with various neurological and muscular symptoms. The aim of this study was to evaluate the pediatric neurological and muscular manifestations of influenza B during a 5-month epidemic at a single center.METHODS:
We retrospectively reviewed the medical records of 355 pediatric patients with laboratory-confirmed influenza B infection.RESULTS:
Neurological and muscular symptoms were exhibited by 28 patients (7.9%). The mean age was 48.7 ± 25.2 months. The mean time between respiratory symptoms and neurological symptoms was 2.2 ± 1.5 days. The most common symptom was seizure (19/28, 67.9%), followed by myositis (5/28, 17.9%), increased intracerebral pressure (1/28, 3.6%), delirium (1/28, 3.6%), and severe headache (1/28, 3.6%). There was one severe case of meningitis with myocarditis (1/28, 3.6%). All seizures were febrile 15 simple febrile seizures (78.9%), three complex febrile seizures (15.8%), and one febrile status epilepticus (5.3%). The mean age of nine patients with their first seizures was 37.9 ± 22.2 months, which was older than the typical age of onset for febrile seizure. All the patients, except one, were treated with oseltamivir. There were no deaths or chronic debilitating sequelae.CONCLUSIONS:
The neurological and muscular complications of influenza B infection in children are relatively mild, and febrile seizure is the most common. However, clinicians should be alert to the possibility of rare severe complications during influenza B outbreaks.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Influenza B virus
/
Influenza, Human
/
Muscular Diseases
/
Nervous System Diseases
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
En
Journal:
Pediatr Neurol
Journal subject:
NEUROLOGIA
/
PEDIATRIA
Year:
2013
Document type:
Article