Uracil-DNA glycosylase expression determines human lung cancer cell sensitivity to pemetrexed.

Weeks, Lachelle D; Fu, Pingfu; Gerson, Stanton L

Weeks, Lachelle D; Fu, Pingfu; Gerson, Stanton L.

Affiliation

Weeks LD; Corresponding Author: Stanton L. Gerson, Case Comprehensive Cancer Center, Wearn 151, 111000 Euclid Avenue, Cleveland, OH 44106. stanton.gerson@case.edu.

Mol Cancer Ther ; 12(10): 2248-60, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23873851

Subject(s)

Drug Resistance, Neoplasm/genetics; Glutamates/administration & dosage; Guanine/analogs & derivatives; Lung Neoplasms/drug therapy; Uracil-DNA Glycosidase/biosynthesis; Cell Line, Tumor; DNA Breaks, Double-Stranded/drug effects; DNA Damage/drug effects; DNA Replication/drug effects; Gene Expression Regulation, Neoplastic/drug effects; Guanine/administration & dosage; Humans; Lung Neoplasms/enzymology; Lung Neoplasms/pathology; Pemetrexed; RNA, Small Interfering

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance, Neoplasm / Uracil-DNA Glycosidase / Glutamates / Guanine / Lung Neoplasms Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2013 Document type: Article Country of publication: United States

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