An apolipoprotein A-I mimetic peptide designed with a reductionist approach stimulates reverse cholesterol transport and reduces atherosclerosis in mice.

Ditiatkovski, Michael; D'Souza, Wilissa; Kesani, Rajitha; Chin-Dusting, Jaye; de Haan, Judy B; Remaley, Alan; Sviridov, Dmitri

Ditiatkovski, Michael; D'Souza, Wilissa; Kesani, Rajitha; Chin-Dusting, Jaye; de Haan, Judy B; Remaley, Alan; Sviridov, Dmitri.

Affiliation

Ditiatkovski M; Baker Heart and Diabetes Institute, Melbourne, Vic., Australia.

PLoS One ; 8(7): e68802, 2013.

Article in En | MEDLINE | ID: mdl-23874769

Subject(s)

Apolipoprotein A-I/chemistry; Atherosclerosis/metabolism; Biomimetics; Cholesterol/metabolism; Peptides/pharmacology; Amino Acid Sequence; Animals; Apolipoprotein A-I/blood; Apolipoproteins E/genetics; Atherosclerosis/drug therapy; Atherosclerosis/pathology; Biological Transport/drug effects; Disease Models, Animal; Inflammation/drug therapy; Inflammation/immunology; Inflammation/pathology; Male; Mice; Mice, Knockout; Oxidation-Reduction/drug effects; Peptides/chemistry; Peptides/pharmacokinetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Cholesterol / Apolipoprotein A-I / Biomimetics / Atherosclerosis Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Australia

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