Mast Cell Stabilizer Ketotifen Inhibits Gouty Inflammation in Rats.

Hsu, Dur-Zong; Chu, Pei-Yi; Chen, Si-Jin; Liu, Ming-Yie

Hsu, Dur-Zong; Chu, Pei-Yi; Chen, Si-Jin; Liu, Ming-Yie.

Affiliation

Hsu DZ; 1Departments of Environmental and Occupational Health, National Cheng Kung University Medical College, Tainan, Taiwan; and 2Sustainable Environment Research Centre, National Cheng Kung University, Tainan, Taiwan.

Am J Ther ; 23(4): e1009-15, 2016.

Article in En | MEDLINE | ID: mdl-23884077

Subject(s)

Anti-Inflammatory Agents/pharmacology; Gout/drug therapy; Inflammation Mediators/metabolism; Inflammation/drug therapy; Ketotifen/pharmacology; Mast Cells/drug effects; Animals; Anti-Inflammatory Agents/administration & dosage; Disease Models, Animal; Dose-Response Relationship, Drug; Gout/chemically induced; Inflammation/chemically induced; Interleukin-1beta/antagonists & inhibitors; Interleukin-6/antagonists & inhibitors; Ketotifen/administration & dosage; Leukocyte Count; Male; Nitric Oxide/antagonists & inhibitors; Rats; Rats, Sprague-Dawley; Uric Acid/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Inflammation Mediators / Gout / Inflammation / Ketotifen / Mast Cells / Anti-Inflammatory Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Am J Ther Journal subject: TERAPEUTICA Year: 2016 Document type: Article Affiliation country: Taiwan Country of publication: United States

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