Targeting density-enhanced phosphatase-1 (DEP-1) with antisense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice.

Krüger, Janine; Trappiel, Manuela; Dagnell, Markus; Stawowy, Philipp; Meyborg, Heike; Böhm, Christian; Bhanot, Sanjay; Ostman, Arne; Kintscher, Ulrich; Kappert, Kai

Krüger, Janine; Trappiel, Manuela; Dagnell, Markus; Stawowy, Philipp; Meyborg, Heike; Böhm, Christian; Bhanot, Sanjay; Ostman, Arne; Kintscher, Ulrich; Kappert, Kai.

Cell Commun Signal ; 11: 49, 2013 Jul 26.

Article in En | MEDLINE | ID: mdl-23889985

Subject(s)

Diet, High-Fat/adverse effects; Obesity/metabolism; Oligonucleotides, Antisense/pharmacology; Receptor-Like Protein Tyrosine Phosphatases, Class 3/metabolism; Adipose Tissue/metabolism; Animals; Cell Line; Insulin/metabolism; Insulin Resistance; Liver/metabolism; Male; Mice, Inbred C57BL; Muscle, Skeletal/metabolism; Obesity/etiology; Organ Specificity; Phenotype; Phosphorylation; Receptor, Insulin/metabolism; Signal Transduction; Tyrosine/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides, Antisense / Receptor-Like Protein Tyrosine Phosphatases, Class 3 / Diet, High-Fat / Obesity Type of study: Etiology_studies Limits: Animals Language: En Journal: Cell Commun Signal Year: 2013 Document type: Article

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