Route of NCLDV evolution: the genomic accordion.
Curr Opin Virol
; 3(5): 595-9, 2013 Oct.
Article
in En
| MEDLINE
| ID: mdl-23896278
ABSTRACT
Nucleo cytoplasmic large DNA virus (NCLDV) superfamily forms a diverse group of viruses that infects a wide range of eukaryotic hosts (e.g. vertebrates, insects, protests, etc.). These viruses are characterized by a huge range in genome size (between 100kb and 1.2Mb), coupled with an extraordinary diverse genomic repertoire. Here I will review some recent results that shed light on the origin and genome evolution of these viruses, introducing the idea that these viruses evolved using a complex process of genomic accordion that imply successive steps of genome expansions (duplication and gene transfers) and genome reduction, in addition to movement and amplification of diverse mobile genetic elements.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genome, Viral
/
Evolution, Molecular
/
DNA Viruses
Language:
En
Journal:
Curr Opin Virol
Year:
2013
Document type:
Article