Properties of a meq-deleted rmd5 Marek's disease vaccine: protection against virulent MDV challenge and induction of lymphoid organ atrophy are simultaneously attenuated by serial passage in vitro.

Lee, Lucy F; Kreager, Kenton; Heidari, Mohammad; Zhang, Huanmin; Lupiani, Blanca; Reddy, Sanjay M; Fadly, Aly

Lee, Lucy F; Kreager, Kenton; Heidari, Mohammad; Zhang, Huanmin; Lupiani, Blanca; Reddy, Sanjay M; Fadly, Aly.

Affiliation

Lee LF; United States Department of Agriculture-Agricultural Research Service, Avian Disease and Oncology Laboratory, East Lansing, MI 48823, USA. leelu@msu.edu

Avian Dis ; 57(2 Suppl): 491-7, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23901766

Subject(s)

Chickens; Herpesvirus 2, Gallid/pathogenicity; Marek Disease Vaccines/immunology; Marek Disease/prevention & control; Oncogene Proteins, Viral/metabolism; Animals; Antibodies, Monoclonal/immunology; Antibodies, Viral/immunology; Atrophy/veterinary; Atrophy/virology; Bursa of Fabricius/pathology; Gene Deletion; Herpesvirus 2, Gallid/genetics; Oncogene Proteins, Viral/genetics; Oncogene Proteins, Viral/immunology; Polymerase Chain Reaction/veterinary; Poultry Diseases/prevention & control; Recombinant Proteins/genetics; Recombinant Proteins/immunology; Recombinant Proteins/metabolism; Serial Passage/veterinary; Spleen/pathology; Thymus Gland/pathology; Viral Vaccines/genetics; Weight Gain/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Chickens / Oncogene Proteins, Viral / Marek Disease / Herpesvirus 2, Gallid / Marek Disease Vaccines Limits: Animals Language: En Journal: Avian Dis Year: 2013 Document type: Article Affiliation country: United States

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