The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.

Lapierre, Louis R; De Magalhaes Filho, C Daniel; McQuary, Philip R; Chu, Chu-Chiao; Visvikis, Orane; Chang, Jessica T; Gelino, Sara; Ong, Binnan; Davis, Andrew E; Irazoqui, Javier E; Dillin, Andrew; Hansen, Malene

Lapierre, Louis R; De Magalhaes Filho, C Daniel; McQuary, Philip R; Chu, Chu-Chiao; Visvikis, Orane; Chang, Jessica T; Gelino, Sara; Ong, Binnan; Davis, Andrew E; Irazoqui, Javier E; Dillin, Andrew; Hansen, Malene.

Affiliation

Lapierre LR; Program of Development and Aging, Del E Webb Neuroscience, Aging and Stem Cell Research Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA, USA.

Nat Commun ; 4: 2267, 2013.

Article in En | MEDLINE | ID: mdl-23925298

Subject(s)

Autophagy; Basic Helix-Loop-Helix Transcription Factors/metabolism; Caenorhabditis elegans Proteins/metabolism; Caenorhabditis elegans/cytology; Caenorhabditis elegans/physiology; Longevity; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism; Cell Nucleus/metabolism; Diet; Female; Lysosomes/metabolism; Male; Mice; Mice, Inbred C57BL; Models, Animal; Mutation/genetics; Sequence Homology, Amino Acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Caenorhabditis elegans / Caenorhabditis elegans Proteins / Basic Helix-Loop-Helix Transcription Factors / Longevity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2013 Document type: Article Affiliation country: United States

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