Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor &#945;.

Crane, Deborah D; Ireland, Robin; Alinger, Joshua B; Small, Pamela; Bosio, Catharine M

Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor α.

Crane, Deborah D; Ireland, Robin; Alinger, Joshua B; Small, Pamela; Bosio, Catharine M.

Affiliation

Crane DD; Immunity to Pulmonary Pathogens Section, Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, USA.

Clin Vaccine Immunol ; 20(10): 1531-40, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23925884

Subject(s)

Francisella tularensis/immunology; Immunosuppressive Agents/immunology; Lipids/immunology; PPAR alpha/antagonists & inhibitors; Pneumonia, Bacterial/immunology; Toll-Like Receptor 2/antagonists & inhibitors; Animals; Cytokines/metabolism; Immunosuppressive Agents/isolation & purification; Lipids/isolation & purification; Macrophages/immunology; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Neutrophils/immunology; PPAR alpha/immunology; Pneumonia, Bacterial/microbiology; Pneumonia, Bacterial/prevention & control; Toll-Like Receptor 2/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Bacterial / PPAR alpha / Toll-Like Receptor 2 / Francisella tularensis / Immunosuppressive Agents / Lipids Limits: Animals Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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