DOCK8 is critical for the survival and function of NKT cells.

Crawford, Greg; Enders, Anselm; Gileadi, Uzi; Stankovic, Sanda; Zhang, Qian; Lambe, Teresa; Crockford, Tanya L; Lockstone, Helen E; Freeman, Alexandra; Arkwright, Peter D; Smart, Joanne M; Ma, Cindy S; Tangye, Stuart G; Goodnow, Christopher C; Cerundolo, Vincenzo; Godfrey, Dale I; Su, Helen C; Randall, Katrina L; Cornall, Richard J

Crawford, Greg; Enders, Anselm; Gileadi, Uzi; Stankovic, Sanda; Zhang, Qian; Lambe, Teresa; Crockford, Tanya L; Lockstone, Helen E; Freeman, Alexandra; Arkwright, Peter D; Smart, Joanne M; Ma, Cindy S; Tangye, Stuart G; Goodnow, Christopher C; Cerundolo, Vincenzo; Godfrey, Dale I; Su, Helen C; Randall, Katrina L; Cornall, Richard J.

Affiliation

Crawford G; Medical Research Council Human Immunology Unit, Weatherall Institute for Molecular Medicine, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom;

Blood ; 122(12): 2052-61, 2013 Sep 19.

Article in En | MEDLINE | ID: mdl-23929855

Subject(s)

Guanine Nucleotide Exchange Factors/genetics; Natural Killer T-Cells/metabolism; Animals; Antigens, CD/metabolism; Antigens, Ly/metabolism; Cell Survival/genetics; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation; Guanine Nucleotide Exchange Factors/metabolism; Humans; Hyaluronan Receptors/metabolism; Immunophenotyping; Integrin alpha Chains/metabolism; Liver/immunology; Liver/metabolism; Lymphocyte Count; Mice; Mice, Knockout; NK Cell Lectin-Like Receptor Subfamily B/metabolism; Natural Killer T-Cells/immunology; Receptors, Antigen, T-Cell/metabolism; Signal Transduction; Thymus Gland/immunology; Thymus Gland/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Guanine Nucleotide Exchange Factors / Natural Killer T-Cells Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2013 Document type: Article Country of publication: United States

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