A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates.

Cooke, Keegan S; Hinkle, Beth; Salimi-Moosavi, Hossein; Foltz, Ian; King, Chadwick; Rathanaswami, Palaniswami; Winters, Aaron; Steavenson, Shirley; Begley, C Glenn; Molineux, Graham; Sasu, Barbra J

Cooke, Keegan S; Hinkle, Beth; Salimi-Moosavi, Hossein; Foltz, Ian; King, Chadwick; Rathanaswami, Palaniswami; Winters, Aaron; Steavenson, Shirley; Begley, C Glenn; Molineux, Graham; Sasu, Barbra J.

Affiliation

Cooke KS; Department of Oncology.

Blood ; 122(17): 3054-61, 2013 Oct 24.

Article in En | MEDLINE | ID: mdl-23945155

Subject(s)

Anemia, Iron-Deficiency/drug therapy; Antibodies, Neutralizing/pharmacology; Erythrocytes/drug effects; Hemoglobins/biosynthesis; Iron/blood; Anemia, Iron-Deficiency/blood; Anemia, Iron-Deficiency/pathology; Animals; Antibodies, Neutralizing/biosynthesis; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Erythrocytes/metabolism; Erythrocytes/pathology; Erythropoiesis/drug effects; Female; Hematinics/pharmacology; Humans; Inflammation/prevention & control; Macaca fascicularis; Male; Mice

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemoglobins / Anemia, Iron-Deficiency / Erythrocytes / Antibodies, Neutralizing / Iron Limits: Animals / Female / Humans / Male Language: En Journal: Blood Year: 2013 Document type: Article Country of publication: United States

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