In vivo release and retinal safety of intravitreal implants of thalidomide in rabbit eyes and antiangiogenic effect on the chorioallantoic membrane.

Fialho, Silvia L; Souza, Pedro A F; Fulgêncio, Gustavo O; Miranda, Murilo M O; Pereira, Bruno G; Haddad, Antonio; Messias, André; Jorge, Rodrigo; Silva-Cunha, Armando

Fialho, Silvia L; Souza, Pedro A F; Fulgêncio, Gustavo O; Miranda, Murilo M O; Pereira, Bruno G; Haddad, Antonio; Messias, André; Jorge, Rodrigo; Silva-Cunha, Armando.

Affiliation

Fialho SL; Pharmaceutical and Biotechnological Development, Ezequiel Dias Foundation , Belo Horizonte , Brazil .

J Drug Target ; 21(9): 837-45, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23952807

Subject(s)

Angiogenesis Inhibitors/administration & dosage; Chorioallantoic Membrane/drug effects; Retina/drug effects; Thalidomide/administration & dosage; Vitreous Body/drug effects; Angiogenesis Inhibitors/adverse effects; Angiogenesis Inhibitors/pharmacokinetics; Angiogenesis Inhibitors/pharmacology; Animals; Chick Embryo; Chorioallantoic Membrane/blood supply; Drug Implants; Electroretinography; Female; Rabbits; Retina/pathology; Solubility; Thalidomide/adverse effects; Thalidomide/pharmacokinetics; Thalidomide/pharmacology; Vitreous Body/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retina / Thalidomide / Vitreous Body / Angiogenesis Inhibitors / Chorioallantoic Membrane Limits: Animals Language: En Journal: J Drug Target Journal subject: FARMACOLOGIA Year: 2013 Document type: Article Affiliation country: Brazil Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google