IglE is an outer membrane-associated lipoprotein essential for intracellular survival and murine virulence of type A Francisella tularensis.

Robertson, Gregory T; Child, Robert; Ingle, Christine; Celli, Jean; Norgard, Michael V

Robertson, Gregory T; Child, Robert; Ingle, Christine; Celli, Jean; Norgard, Michael V.

Affiliation

Robertson GT; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Infect Immun ; 81(11): 4026-40, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23959721

Subject(s)

Francisella tularensis/pathogenicity; Lipoproteins/metabolism; Membrane Proteins/metabolism; Microbial Viability; Tularemia/pathology; Virulence Factors/metabolism; Animals; Cell Line; Disease Models, Animal; Female; Francisella tularensis/chemistry; Francisella tularensis/genetics; Gene Knockout Techniques; Genetic Complementation Test; Genomic Islands; Lipoproteins/chemistry; Lipoproteins/genetics; Macrophages/microbiology; Membrane Proteins/chemistry; Membrane Proteins/genetics; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Weight; Tularemia/microbiology; Virulence; Virulence Factors/chemistry; Virulence Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tularemia / Virulence Factors / Microbial Viability / Francisella tularensis / Lipoproteins / Membrane Proteins Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Infect Immun Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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