Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence.

Sadaie, Mahito; Salama, Rafik; Carroll, Thomas; Tomimatsu, Kosuke; Chandra, Tamir; Young, Andrew R J; Narita, Masako; Pérez-Mancera, Pedro A; Bennett, Dorothy C; Chong, Heung; Kimura, Hiroshi; Narita, Masashi

Sadaie, Mahito; Salama, Rafik; Carroll, Thomas; Tomimatsu, Kosuke; Chandra, Tamir; Young, Andrew R J; Narita, Masako; Pérez-Mancera, Pedro A; Bennett, Dorothy C; Chong, Heung; Kimura, Hiroshi; Narita, Masashi.

Affiliation

Sadaie M; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom.

Genes Dev ; 27(16): 1800-8, 2013 Aug 15.

Article in En | MEDLINE | ID: mdl-23964094

Subject(s)

Cellular Senescence/genetics; Chromatin Assembly and Disassembly/genetics; Heterochromatin/metabolism; Lamin Type B/metabolism; Cell Line; Cell Nucleus/metabolism; Cells, Cultured; Gene Expression Regulation; Heterochromatin/chemistry; Histones/metabolism; Lamin Type B/genetics; Protein Binding; Protein Structure, Tertiary

Key words

Lamin B1; epigenetics; senescence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heterochromatin / Cellular Senescence / Lamin Type B / Chromatin Assembly and Disassembly Language: En Journal: Genes Dev Journal subject: BIOLOGIA MOLECULAR Year: 2013 Document type: Article Affiliation country: United kingdom Country of publication: United States

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