Biphasic myosin II light chain activation during clot retraction.

Egot, Marion; Kauskot, Alexandre; Lasne, Dominique; Gaussem, Pascale; Bachelot-Loza, Christilla

Egot, Marion; Kauskot, Alexandre; Lasne, Dominique; Gaussem, Pascale; Bachelot-Loza, Christilla.

Affiliation

Egot M; Dr Christilla Bachelot-Loza, INSERM UMR_S U765, Université Paris Descartes, Faculté de Pharmacie, 4 avenue de l'Observatoire, 75006 Paris, France, Tel : +33 153739619, E-mail: christilla.bachelot-loza@parisdescartes.fr.

Thromb Haemost ; 110(6): 1215-22, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23965920

Subject(s)

Actin Cytoskeleton/metabolism; Blood Platelets/physiology; Myosin Light Chains/metabolism; Myosin Type II/metabolism; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism; Actomyosin/metabolism; Amides/pharmacology; Aminoquinolines/pharmacology; Azepines/pharmacology; Cells, Cultured; Clot Retraction/physiology; Humans; Kinetics; Myosin-Light-Chain Kinase/antagonists & inhibitors; Naphthalenes/pharmacology; Phosphorylation/drug effects; Pyridines/pharmacology; Pyrimidines/pharmacology; Signal Transduction/drug effects; Wound Healing; rac1 GTP-Binding Protein/antagonists & inhibitors; rho-Associated Kinases/antagonists & inhibitors; rhoA GTP-Binding Protein/metabolism

Key words

Clot retraction; cytoskeleton; kinases; myosin light chain; signal transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Actin Cytoskeleton / Platelet Glycoprotein GPIIb-IIIa Complex / Myosin Light Chains / Myosin Type II Limits: Humans Language: En Journal: Thromb Haemost Year: 2013 Document type: Article

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