Formulation design and optimization for the improvement of nystatin-loaded lipid intravenous emulsion.

Marín-Quintero, Deiry; Fernández-Campos, Francisco; Calpena-Campmany, Ana C; Montes-López, María J; Clares-Naveros, Beatriz; Del Pozo-Carrascosa, Alfonso

Marín-Quintero, Deiry; Fernández-Campos, Francisco; Calpena-Campmany, Ana C; Montes-López, María J; Clares-Naveros, Beatriz; Del Pozo-Carrascosa, Alfonso.

Affiliation

Marín-Quintero D; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Barcelona, Barcelona, Spain.

J Pharm Sci ; 102(11): 4015-23, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23970386

Subject(s)

Antifungal Agents/administration & dosage; Delayed-Action Preparations/chemistry; Glycerol/chemistry; Nystatin/administration & dosage; Phospholipids/chemistry; Polyethylene Glycols/chemistry; Soybean Oil/chemistry; Stearic Acids/chemistry; Antifungal Agents/pharmacology; Aspergillosis/drug therapy; Aspergillus/drug effects; Candida albicans/drug effects; Candidiasis/drug therapy; Emulsions/chemistry; Humans; Injections, Intravenous; Nystatin/pharmacology

Key words

aspergillus; candida; drug design; emulsion; injectables; lipids; mathematical model; nystatin; surfactants

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Polyethylene Glycols / Stearic Acids / Soybean Oil / Nystatin / Delayed-Action Preparations / Glycerol / Antifungal Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Pharm Sci Year: 2013 Document type: Article Affiliation country: Spain

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