NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies.

Choi, Hyo Jei Claudia; Lin, Jia-Ren; Vannier, Jean-Baptiste; Slaats, Gisela G; Kile, Andrew C; Paulsen, Renee D; Manning, Danielle K; Beier, David R; Giles, Rachel H; Boulton, Simon J; Cimprich, Karlene A

Choi, Hyo Jei Claudia; Lin, Jia-Ren; Vannier, Jean-Baptiste; Slaats, Gisela G; Kile, Andrew C; Paulsen, Renee D; Manning, Danielle K; Beier, David R; Giles, Rachel H; Boulton, Simon J; Cimprich, Karlene A.

Affiliation

Choi HJ; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94025, USA.

Mol Cell ; 51(4): 423-39, 2013 Aug 22.

Article in En | MEDLINE | ID: mdl-23973373

Subject(s)

Cell Cycle Proteins/metabolism; Cilia/pathology; Cyclin-Dependent Kinases/metabolism; DNA Replication/genetics; Polycystic Kidney Diseases/pathology; Protein Kinases/metabolism; Protein Serine-Threonine Kinases/metabolism; S Phase/physiology; Animals; Ataxia Telangiectasia Mutated Proteins; Cell Culture Techniques; Cell Cycle Checkpoints; Cell Cycle Proteins/genetics; Cilia/metabolism; Cyclin-Dependent Kinases/genetics; DNA Damage/genetics; Genomic Instability; Humans; Mice; Mutation/genetics; NIMA-Related Kinases; Phosphorylation; Polycystic Kidney Diseases/metabolism; Protein Kinases/chemistry; Protein Kinases/genetics; Protein Serine-Threonine Kinases/genetics; Stress, Physiological

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / S Phase / Cilia / Protein Serine-Threonine Kinases / Cyclin-Dependent Kinases / Cell Cycle Proteins / DNA Replication / Polycystic Kidney Diseases Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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