Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.

Viola, Manuela; Bartolini, Barbara; Vigetti, Davide; Karousou, Evgenia; Moretto, Paola; Deleonibus, Sara; Sawamura, Tatsuya; Wight, Thomas N; Hascall, Vincent C; De Luca, Giancarlo; Passi, Alberto

Viola, Manuela; Bartolini, Barbara; Vigetti, Davide; Karousou, Evgenia; Moretto, Paola; Deleonibus, Sara; Sawamura, Tatsuya; Wight, Thomas N; Hascall, Vincent C; De Luca, Giancarlo; Passi, Alberto.

Affiliation

Viola M; From the Dipartimento di Scienze Chirurgiche e Morfologiche, Università degli Studi dell'Insubria, via J. H. Dunant 5, 21100 Varese, Italy.

J Biol Chem ; 288(41): 29595-603, 2013 Oct 11.

Article in En | MEDLINE | ID: mdl-23979132

Subject(s)

Cell Movement/drug effects; Hyaluronic Acid/biosynthesis; Lipoproteins, LDL/pharmacology; Myocytes, Smooth Muscle/drug effects; Antibodies/immunology; Antibodies/pharmacology; Aorta/cytology; Cell Adhesion/drug effects; Cell Survival/drug effects; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Extracellular Matrix/metabolism; Gene Expression/drug effects; Glucuronosyltransferase/genetics; Humans; Hyaluronan Synthases; Lipoproteins, LDL/metabolism; Monocytes/drug effects; Monocytes/metabolism; Myocytes, Smooth Muscle/metabolism; Oxidation-Reduction; Reverse Transcriptase Polymerase Chain Reaction; Scavenger Receptors, Class E/antagonists & inhibitors; Scavenger Receptors, Class E/immunology; Scavenger Receptors, Class E/metabolism; U937 Cells

Key words

Atherosclerosis; Cholesterol; Glycosaminoglycan; Scavenger Receptor; Vascular Smooth Muscle Cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / Myocytes, Smooth Muscle / Hyaluronic Acid / Lipoproteins, LDL Limits: Humans Language: En Journal: J Biol Chem Year: 2013 Document type: Article Affiliation country: Italy Country of publication: United States

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