Apigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function.

Duarte, Silvia; Arango, Daniel; Parihar, Arti; Hamel, Patrice; Yasmeen, Rumana; Doseff, Andrea I

Duarte, Silvia; Arango, Daniel; Parihar, Arti; Hamel, Patrice; Yasmeen, Rumana; Doseff, Andrea I.

Affiliation

Duarte S; Department of Molecular Genetics, the Ohio State University, Columbus, OH 43210, USA. duartesanmiguel.1@osu.edu

Int J Mol Sci ; 14(9): 17664-79, 2013 Aug 28.

Article in En | MEDLINE | ID: mdl-23989609

Subject(s)

Apigenin/pharmacology; Caspase 3/metabolism; Inflammation/chemically induced; Lipopolysaccharides/pharmacology; Animals; Apoptosis/drug effects; Cattle; Cell Survival/drug effects; Cells, Cultured; Inflammation/metabolism; Mitochondria/drug effects; Mitochondria/metabolism; Reactive Oxygen Species/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lipopolysaccharides / Apigenin / Caspase 3 / Inflammation Limits: Animals Language: En Journal: Int J Mol Sci Year: 2013 Document type: Article Affiliation country: United States

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