ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation.

Zumwalde, Nicholas A; Domae, Eisuke; Mescher, Matthew F; Shimizu, Yoji

Zumwalde, Nicholas A; Domae, Eisuke; Mescher, Matthew F; Shimizu, Yoji.

Affiliation

Zumwalde NA; Department of Laboratory Medicine and Pathology, Center for Immunology, Masonic Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455.

J Immunol ; 191(7): 3681-93, 2013 Oct 01.

Article in En | MEDLINE | ID: mdl-23997225

Subject(s)

CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; Cell Differentiation/immunology; Intercellular Adhesion Molecule-1/metabolism; Lymphocyte Activation/immunology; Animals; Antigens/immunology; CD8-Positive T-Lymphocytes/cytology; CTLA-4 Antigen/genetics; CTLA-4 Antigen/metabolism; Cell Communication/immunology; Cell Differentiation/genetics; Dendritic Cells/immunology; Dendritic Cells/metabolism; Gene Expression Regulation; Intercellular Adhesion Molecule-1/genetics; Interferon-gamma/biosynthesis; Interleukin-12/pharmacology; Lymphocyte Activation/drug effects; Lymphocyte Activation/genetics; Mice; T-Lymphocyte Subsets/cytology; T-Lymphocyte Subsets/drug effects; T-Lymphocyte Subsets/immunology; T-Lymphocyte Subsets/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Activation / Cell Differentiation / Intercellular Adhesion Molecule-1 / CD8-Positive T-Lymphocytes Limits: Animals Language: En Journal: J Immunol Year: 2013 Document type: Article Country of publication: United States

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