Clot retraction is mediated by factor XIII-dependent fibrin-&#945;IIbß3-myosin axis in platelet sphingomyelin-rich membrane rafts.

Kasahara, Kohji; Kaneda, Mizuho; Miki, Toshiaki; Iida, Kazuko; Sekino-Suzuki, Naoko; Kawashima, Ikuo; Suzuki, Hidenori; Shimonaka, Motoyuki; Arai, Morio; Ohno-Iwashita, Yoshiko; Kojima, Soichi; Abe, Mitsuhiro; Kobayashi, Toshihide; Okazaki, Toshiro; Souri, Masayoshi; Ichinose, Akitada; Yamamoto, Naomasa

Clot retraction is mediated by factor XIII-dependent fibrin-αIIbß3-myosin axis in platelet sphingomyelin-rich membrane rafts.

Kasahara, Kohji; Kaneda, Mizuho; Miki, Toshiaki; Iida, Kazuko; Sekino-Suzuki, Naoko; Kawashima, Ikuo; Suzuki, Hidenori; Shimonaka, Motoyuki; Arai, Morio; Ohno-Iwashita, Yoshiko; Kojima, Soichi; Abe, Mitsuhiro; Kobayashi, Toshihide; Okazaki, Toshiro; Souri, Masayoshi; Ichinose, Akitada; Yamamoto, Naomasa.

Affiliation

Kasahara K; Laboratory of Biomembrane and.

Blood ; 122(19): 3340-8, 2013 Nov 07.

Article in En | MEDLINE | ID: mdl-24002447

Subject(s)

Blood Platelets/metabolism; Clot Retraction/genetics; Factor XIII/metabolism; Fibrin/metabolism; Myosins/metabolism; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism; Sphingomyelins/metabolism; Animals; Blood Coagulation/drug effects; Blood Coagulation/genetics; Blood Platelets/cytology; Blood Platelets/drug effects; Clot Retraction/drug effects; Factor XIII/genetics; Fibrin/genetics; Gene Expression; Humans; Membrane Microdomains/chemistry; Membrane Microdomains/drug effects; Membrane Microdomains/metabolism; Mice; Mice, Knockout; Myosins/genetics; Platelet Glycoprotein GPIIb-IIIa Complex/genetics; Protein Transport; Signal Transduction; Thrombin/pharmacology; Transferases (Other Substituted Phosphate Groups)/deficiency; Transferases (Other Substituted Phosphate Groups)/genetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sphingomyelins / Blood Platelets / Factor XIII / Fibrin / Myosins / Clot Retraction / Platelet Glycoprotein GPIIb-IIIa Complex Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2013 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google