Identification of 6-octadecynoic acid from a methanol extract of Marrubium vulgare L. as a peroxisome proliferator-activated receptor Î³ agonist.

Ohtera, Anna; Miyamae, Yusaku; Nakai, Naomi; Kawachi, Atsushi; Kawada, Kiyokazu; Han, Junkyu; Isoda, Hiroko; Neffati, Mohamed; Akita, Toru; Maejima, Kazuhiro; Masuda, Seiji; Kambe, Taiho; Mori, Naoki; Irie, Kazuhiro; Nagao, Masaya

Ohtera, Anna; Miyamae, Yusaku; Nakai, Naomi; Kawachi, Atsushi; Kawada, Kiyokazu; Han, Junkyu; Isoda, Hiroko; Neffati, Mohamed; Akita, Toru; Maejima, Kazuhiro; Masuda, Seiji; Kambe, Taiho; Mori, Naoki; Irie, Kazuhiro; Nagao, Masaya.

Affiliation

Ohtera A; Graduate School of Biostudies, Kyoto University, Kyoto 606-8502, Japan.

Biochem Biophys Res Commun ; 440(2): 204-9, 2013 Oct 18.

Article in En | MEDLINE | ID: mdl-24025677

Subject(s)

Fatty Acids, Monounsaturated/pharmacology; Hepatic Stellate Cells/drug effects; PPAR gamma/agonists; Plant Extracts/pharmacology; 3T3-L1 Cells; Alkynes/pharmacology; Animals; Fatty Acids, Unsaturated/pharmacology; Humans; Marrubium/chemistry; Mice

Key words

15-deoxy-Δ12,14-prostaglandin J(2); 15d-PDJ(2); 6-ODA; 6-Octadecynoic acid; 6-octadecynoic acid; 9-ODA; 9-octadecynoic acid; Lipid accumulation; Marrubium vulgare L.; PPARÎ³; Peroxisome proliferator-activated receptor Î³ (PPARÎ³); peroxisome proliferator-activated receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fatty Acids, Monounsaturated / Plant Extracts / PPAR gamma / Hepatic Stellate Cells Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2013 Document type: Article Affiliation country: Japan Country of publication: United States

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