Subtypes of type I IFN differentially enhance cytokine expression by suboptimally stimulated CD4(+) T cells.

Hillyer, Philippa; Raviv, Nataly; Gold, Doria M; Dougherty, Danielle; Liu, Jie; Johnson, Teresa R; Graham, Barney S; Rabin, Ronald L

Hillyer, Philippa; Raviv, Nataly; Gold, Doria M; Dougherty, Danielle; Liu, Jie; Johnson, Teresa R; Graham, Barney S; Rabin, Ronald L.

Affiliation

Hillyer P; Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic and Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, US Food and Drug Administration, Bethesda, MD, USA.

Eur J Immunol ; 43(12): 3197-208, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24030809

Subject(s)

Interferon-alpha/immunology; Th1 Cells/immunology; Th2 Cells/immunology; Bacterial Proteins/chemistry; Bacterial Proteins/immunology; Bacterial Proteins/pharmacology; Cytomegalovirus/chemistry; Cytomegalovirus/immunology; Enterotoxins/chemistry; Enterotoxins/immunology; Enterotoxins/pharmacology; Female; Gene Expression Regulation/drug effects; Gene Expression Regulation/immunology; Humans; Immunologic Memory/drug effects; Immunologic Memory/immunology; Interferon-gamma/immunology; Interleukin-2/immunology; Interleukin-4/immunology; Male; Peptides/chemistry; Peptides/immunology; Peptides/pharmacology; Respiratory Syncytial Viruses/chemistry; Respiratory Syncytial Viruses/immunology; Staphylococcus aureus/chemistry; Staphylococcus aureus/immunology; Th1 Cells/cytology; Th2 Cells/cytology; Viral Proteins/chemistry; Viral Proteins/immunology; Viral Proteins/pharmacology

Key words

CD4+ T cells; Cytokine expression; IFNs; Memory cells; Th cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-alpha / Th2 Cells / Th1 Cells Limits: Female / Humans / Male Language: En Journal: Eur J Immunol Year: 2013 Document type: Article Affiliation country: United States

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