7,8-dihydroxyflavone, a small-molecule tropomyosin-related kinase B (TrkB) agonist, attenuates cerebral ischemia and reperfusion injury in rats.

Wang, Bing; Wu, Nan; Liang, Feng; Zhang, Shuqin; Ni, Weimin; Cao, Yunxing; Xia, Dongjian; Xi, Huanjiu

Wang, Bing; Wu, Nan; Liang, Feng; Zhang, Shuqin; Ni, Weimin; Cao, Yunxing; Xia, Dongjian; Xi, Huanjiu.

Affiliation

Wang B; Department of Human Anatomy, Histology and Embryology, China Medical University, 92 Bei'er Road, Shenyang, 110001, Liaoning, People's Republic of China.

J Mol Histol ; 45(2): 129-40, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24045895

Subject(s)

Enzyme Activators/pharmacology; Flavones/pharmacology; Infarction, Middle Cerebral Artery/drug therapy; Receptor, trkB/metabolism; Reperfusion Injury/prevention & control; Animals; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Activators/therapeutic use; Flavones/therapeutic use; Glutathione/metabolism; Glutathione Peroxidase/metabolism; Male; Malondialdehyde/metabolism; Nitric Oxide/metabolism; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, trkB/agonists; Superoxide Dismutase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reperfusion Injury / Infarction, Middle Cerebral Artery / Receptor, trkB / Enzyme Activators / Flavones Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Mol Histol Journal subject: HISTOCITOQUIMICA Year: 2014 Document type: Article

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