Self-crosslinked human serum albumin nanocarriers for systemic delivery of polymerized siRNA to tumors.

Son, Sohee; Song, Seungyong; Lee, So Jin; Min, Solki; Kim, Sun Ah; Yhee, Ji Young; Huh, Myung Sook; Chan Kwon, Ick; Jeong, Seo Young; Byun, Youngro; Kim, Sun Hwa; Kim, Kwangmeyung

Son, Sohee; Song, Seungyong; Lee, So Jin; Min, Solki; Kim, Sun Ah; Yhee, Ji Young; Huh, Myung Sook; Chan Kwon, Ick; Jeong, Seo Young; Byun, Youngro; Kim, Sun Hwa; Kim, Kwangmeyung.

Affiliation

Son S; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 6, Seongbuk-gu, Seoul 136-791, South Korea.

Biomaterials ; 34(37): 9475-85, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24050874

Subject(s)

Drug Carriers/chemistry; Neoplasms/therapy; RNA Interference; RNA, Small Interfering/administration & dosage; Serum Albumin/chemistry; Animals; Cell Line, Tumor; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Neoplasms/blood supply; Neoplasms/genetics; Neovascularization, Pathologic/genetics; Neovascularization, Pathologic/therapy; Polymerization; RNA, Small Interfering/chemistry; RNA, Small Interfering/genetics; RNA, Small Interfering/therapeutic use; Sulfhydryl Compounds/chemistry; Vascular Endothelial Growth Factor A/genetics

Key words

Cancer therapy; Human serum albumin; Polymerized siRNA; Protein based carrier; RNAi

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serum Albumin / Drug Carriers / RNA, Small Interfering / RNA Interference / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Biomaterials Year: 2013 Document type: Article Affiliation country: South Korea Country of publication: Netherlands

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