Your browser doesn't support javascript.
loading
A glyco-gold nanoparticle based assay for α-2,8-polysialyltransferase from Neisseria meningitidis.
Yu, Ching-Ching; Huang, Li-De; Kwan, David H; Wakarchuk, Warren W; Withers, Stephen G; Lin, Chun-Cheng.
Affiliation
  • Yu CC; Department of Chemistry, National Tsing Hua University, 101, Sec. 2, Kuang Fu Rd., Hsinchu, 30013, Taiwan. cclin66@mx.nthu.edu.tw.
Chem Commun (Camb) ; 49(86): 10166-8, 2013 Oct 03.
Article in En | MEDLINE | ID: mdl-24051967
ABSTRACT
We designed a novel strategy for sensitively detecting the activity of α-2,8-polysialyltransferase (PST) by a combination of ganglioside GD3 functionalized gold nanoparticles and inactive endosialidase. We anticipate that this new method will facilitate the search for PST inhibitors as well as for improved mutant forms of PST in directed evolution experiments.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sialyltransferases / Biosensing Techniques / Metal Nanoparticles / Gangliosides / Gold / Neisseria meningitidis Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: Taiwan
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sialyltransferases / Biosensing Techniques / Metal Nanoparticles / Gangliosides / Gold / Neisseria meningitidis Language: En Journal: Chem Commun (Camb) Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: Taiwan