Aggressive chemotherapy and the selection of drug resistant pathogens.

Huijben, Silvie; Bell, Andrew S; Sim, Derek G; Tomasello, Danielle; Mideo, Nicole; Day, Troy; Read, Andrew F

Huijben, Silvie; Bell, Andrew S; Sim, Derek G; Tomasello, Danielle; Mideo, Nicole; Day, Troy; Read, Andrew F.

Affiliation

Huijben S; Center for Infectious Disease Dynamics, Departments of Biology and Entomology, Pennsylvania State University, University Park, Pennsylvania, United States of America.

PLoS Pathog ; 9(9): e1003578, 2013 Sep.

Article in En | MEDLINE | ID: mdl-24068922

Subject(s)

Antimalarials/administration & dosage; Drug Resistance; Malaria/drug therapy; Models, Biological; Plasmodium chabaudi/drug effects; Selection, Genetic/drug effects; Animals; Antimalarials/adverse effects; Antimalarials/pharmacology; Antimalarials/therapeutic use; Clone Cells; Dose-Response Relationship, Drug; Erythrocytes/drug effects; Erythrocytes/parasitology; Female; Malaria/blood; Malaria/parasitology; Mice, Inbred C57BL; Parasite Egg Count; Plasmodium chabaudi/genetics; Plasmodium chabaudi/growth & development; Plasmodium chabaudi/pathogenicity; Pyrimethamine/administration & dosage; Pyrimethamine/adverse effects; Pyrimethamine/pharmacology; Pyrimethamine/therapeutic use; Virulence/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Selection, Genetic / Drug Resistance / Plasmodium chabaudi / Malaria / Models, Biological / Antimalarials Limits: Animals Language: En Journal: PLoS Pathog Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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