Recipient leukocyte infusion enhances the local and systemic graft-versus-neuroblastoma effect of allogeneic bone marrow transplantation in mice.

Willems, Leen; Fevery, Sabien; Sprangers, Ben; Rutgeerts, Omer; Lenaerts, Caroline; Ibrahimi, Abdelilah; Gijsbers, Rik; Van Gool, Stefaan; Waer, Mark; Billiau, An D

Willems, Leen; Fevery, Sabien; Sprangers, Ben; Rutgeerts, Omer; Lenaerts, Caroline; Ibrahimi, Abdelilah; Gijsbers, Rik; Van Gool, Stefaan; Waer, Mark; Billiau, An D.

Affiliation

Willems L; Laboratory of Experimental Transplantation, KU Leuven, Herestraat 49, box 811, 3000, Leuven, Belgium, leen.willems@med.kuleuven.be.

Cancer Immunol Immunother ; 62(11): 1733-44, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24081484

Subject(s)

Bone Marrow Transplantation/methods; Graft vs Host Disease/immunology; Leukocyte Transfusion/methods; Neuroblastoma/immunology; Animals; CD8-Positive T-Lymphocytes/immunology; CD8-Positive T-Lymphocytes/metabolism; Cell Line, Tumor; Graft Rejection/immunology; Granzymes/immunology; Granzymes/metabolism; Host vs Graft Reaction/immunology; Interferon-gamma/immunology; Interferon-gamma/metabolism; Kaplan-Meier Estimate; Killer Cells, Natural/immunology; Killer Cells, Natural/metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neuroblastoma/pathology; Neuroblastoma/therapy; Transplantation Chimera/immunology; Transplantation, Homologous; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Transplantation / Leukocyte Transfusion / Graft vs Host Disease / Neuroblastoma Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2013 Document type: Article

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