The viral ubiquitin ligase ICP0 is neither sufficient nor necessary for degradation of the cellular DNA sensor IFI16 during herpes simplex virus 1 infection.

Cuchet-Lourenço, Delphine; Anderson, Gail; Sloan, Elizabeth; Orr, Anne; Everett, Roger D

Cuchet-Lourenço, Delphine; Anderson, Gail; Sloan, Elizabeth; Orr, Anne; Everett, Roger D.

Affiliation

Cuchet-Lourenço D; MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom.

J Virol ; 87(24): 13422-32, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24089555

Subject(s)

Herpes Simplex/metabolism; Herpesvirus 1, Human/enzymology; Immediate-Early Proteins/metabolism; Nuclear Proteins/metabolism; Phosphoproteins/metabolism; Ubiquitin-Protein Ligases/metabolism; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/metabolism; Co-Repressor Proteins; Herpes Simplex/genetics; Herpes Simplex/virology; Herpesvirus 1, Human/genetics; Herpesvirus 1, Human/physiology; Host-Pathogen Interactions; Humans; Immediate-Early Proteins/genetics; Molecular Chaperones; Nuclear Proteins/genetics; Phosphoproteins/genetics; Promyelocytic Leukemia Protein; Proteolysis; Transcription Factors/genetics; Transcription Factors/metabolism; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism; Ubiquitin-Protein Ligases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Nuclear Proteins / Immediate-Early Proteins / Herpesvirus 1, Human / Ubiquitin-Protein Ligases / Herpes Simplex Limits: Humans Language: En Journal: J Virol Year: 2013 Document type: Article Affiliation country: United kingdom Country of publication: United States

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