The 30-kDa and 38-kDa antigens from Mycobacterium tuberculosis induce partial maturation of human dendritic cells shifting CD4(+) T cell responses towards IL-4 production.

Heuer, Marion; Behlich, Anna-Sophie; Lee, Ji-Sook; Ribechini, Eliana; Jo, Eun-Kyeong; Lutz, Manfred B

Heuer, Marion; Behlich, Anna-Sophie; Lee, Ji-Sook; Ribechini, Eliana; Jo, Eun-Kyeong; Lutz, Manfred B.

Affiliation

Heuer M; Institute of Virology and Immunobiology, University of Würzburg, Würzburg, Germany. m.lutz@vim.uni-wuerzburg.de.

BMC Immunol ; 14: 48, 2013 Oct 03.

Article in En | MEDLINE | ID: mdl-24089996

Subject(s)

Antigens, Bacterial/immunology; CD4-Positive T-Lymphocytes/immunology; Dendritic Cells/immunology; Interleukin-4/immunology; Antigens, Bacterial/chemistry; Antigens, Bacterial/pharmacology; Antigens, CD/immunology; Antigens, CD/metabolism; B7-1 Antigen/immunology; B7-1 Antigen/metabolism; B7-2 Antigen/immunology; B7-2 Antigen/metabolism; CD4-Positive T-Lymphocytes/drug effects; CD4-Positive T-Lymphocytes/metabolism; Cell Differentiation/drug effects; Cell Differentiation/immunology; Cells, Cultured; Dendritic Cells/drug effects; Dendritic Cells/metabolism; Flow Cytometry; Humans; Immunoglobulins/immunology; Immunoglobulins/metabolism; Interleukin-10/immunology; Interleukin-10/metabolism; Interleukin-12 Subunit p40/immunology; Interleukin-12 Subunit p40/metabolism; Interleukin-4/metabolism; Interleukin-6/immunology; Interleukin-6/metabolism; Lipopolysaccharides/immunology; Lipopolysaccharides/pharmacology; Membrane Glycoproteins/immunology; Membrane Glycoproteins/metabolism; Molecular Weight; Mycobacterium tuberculosis/classification; Mycobacterium tuberculosis/immunology; CD83 Antigen

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / CD4-Positive T-Lymphocytes / Interleukin-4 / Antigens, Bacterial Language: En Journal: BMC Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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