The establishment and validation of efficient assays for anti-IIa and anti-Xa activities of heparin sodium and heparin calcium.

Suzuki, Takuo; Ishii-Watabe, Akiko; Hashii, Noritaka; Nakagawa, Yukari; Takahashi, Tomoko; Ebisawa, Akiko; Nishi, Seiichi; Fujita, Naho; Bando, Aya; Sekimoto, Yuko; Miyata, Kazuyoshi; Endo, Toshio; Otsu, Takuma; Sugimoto, Shiori; Kondou, Tadashi; Fujita, Yuji; Miyanaga, Naoyuki; Mashimo, Masahiro; Shimada, Norihiko; Yoden, Hikaru; Shimamura, Hideo; Kurata, Yasunori; Koyama, Sadatoshi; Kawasaki, Nana

Suzuki, Takuo; Ishii-Watabe, Akiko; Hashii, Noritaka; Nakagawa, Yukari; Takahashi, Tomoko; Ebisawa, Akiko; Nishi, Seiichi; Fujita, Naho; Bando, Aya; Sekimoto, Yuko; Miyata, Kazuyoshi; Endo, Toshio; Otsu, Takuma; Sugimoto, Shiori; Kondou, Tadashi; Fujita, Yuji; Miyanaga, Naoyuki; Mashimo, Masahiro; Shimada, Norihiko; Yoden, Hikaru; Shimamura, Hideo; Kurata, Yasunori; Koyama, Sadatoshi; Kawasaki, Nana.

Affiliation

Suzuki T; National Institute of Health Sciences, Japan. Electronic address: tsuzuki@nihs.go.jp.

Biologicals ; 41(6): 415-23, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24095600

Subject(s)

Factor Xa Inhibitors; Heparin/pharmacology; Prothrombin/antagonists & inhibitors; Anticoagulants/metabolism; Anticoagulants/pharmacology; Antithrombins/metabolism; Factor Xa/metabolism; Heparin/metabolism; Humans; Oligopeptides/metabolism; Prothrombin/metabolism; Reproducibility of Results; Technology, Pharmaceutical/methods

Key words

Anti-IIa assay; Anti-Xa assay; Heparin; Quality control

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prothrombin / Heparin / Factor Xa Inhibitors Limits: Humans Language: En Journal: Biologicals Journal subject: ALERGIA E IMUNOLOGIA Year: 2013 Document type: Article

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