Structural insights into neutrophilic migration revealed by the crystal structure of the chemokine receptor CXCR2 in complex with the first PDZ domain of NHERF1.

Lu, Guorong; Wu, Yanning; Jiang, Yuanyuan; Wang, Shuo; Hou, Yuning; Guan, Xiaoqing; Brunzelle, Joseph; Sirinupong, Nualpun; Sheng, Shijie; Li, Chunying; Yang, Zhe

Lu, Guorong; Wu, Yanning; Jiang, Yuanyuan; Wang, Shuo; Hou, Yuning; Guan, Xiaoqing; Brunzelle, Joseph; Sirinupong, Nualpun; Sheng, Shijie; Li, Chunying; Yang, Zhe.

Affiliation

Lu G; Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, Michigan, United States of America.

PLoS One ; 8(10): e76219, 2013.

Article in En | MEDLINE | ID: mdl-24098448

Subject(s)

PDZ Domains; Phosphoproteins/chemistry; Receptors, Interleukin-8B/chemistry; Sodium-Hydrogen Exchangers/chemistry; Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Drug Design; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Neutrophils/immunology; Neutrophils/metabolism; Phosphoproteins/metabolism; Protein Binding; Protein Conformation; Receptors, Interleukin-8B/metabolism; Sequence Alignment; Sodium-Hydrogen Exchangers/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Sodium-Hydrogen Exchangers / Receptors, Interleukin-8B / PDZ Domains Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: United States

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