Cardio-metabolic effectsof HIV protease inhibitors (lopinavir/ritonavir).

Reyskens, Kathleen M S E; Fisher, Tarryn-Lee; Schisler, Jonathan C; O'Connor, Wendi G; Rogers, Arlin B; Willis, Monte S; Planesse, Cynthia; Boyer, Florence; Rondeau, Philippe; Bourdon, Emmanuel; Essop, M Faadiel

Reyskens, Kathleen M S E; Fisher, Tarryn-Lee; Schisler, Jonathan C; O'Connor, Wendi G; Rogers, Arlin B; Willis, Monte S; Planesse, Cynthia; Boyer, Florence; Rondeau, Philippe; Bourdon, Emmanuel; Essop, M Faadiel.

Affiliation

Reyskens KM; Cardio-Metabolic Research Group, Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa.

PLoS One ; 8(9): e73347, 2013.

Article in En | MEDLINE | ID: mdl-24098634

Subject(s)

Antiretroviral Therapy, Highly Active/methods; HIV Infections/drug therapy; HIV Protease Inhibitors/pharmacology; Myocardium/metabolism; Oxidative Stress/drug effects; Analysis of Variance; Animals; Blotting, Western; Calcineurin/metabolism; Calcium-Binding Proteins/metabolism; Cholesterol, LDL/blood; Connexin 43/metabolism; DNA Primers/genetics; Drug Combinations; Gene Expression Regulation, Enzymologic/drug effects; Liver/metabolism; Lopinavir/pharmacology; Male; NFATC Transcription Factors/metabolism; Proteasome Endopeptidase Complex/drug effects; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Ritonavir/pharmacology; Triglycerides/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV Protease Inhibitors / Oxidative Stress / Antiretroviral Therapy, Highly Active / Myocardium Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: South Africa Country of publication: United States

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